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osteomyelitis acuta - onbekende verwekker

Advices

≥ 18 years
Priority Medication Remarks
Priority:
1st choice
Medication:

flucloxacilline iv 1000mg 6dd 4 to 6 weeks

Priority:
1st choice
Medication:

flucloxacilline iv 1000mg 6dd 4 to 6 weeks

+

aminoglycoside iv 1dd 3 to 5 days

Priority:
1st choice alternative
Medication:

cefuroxim iv 1500mg 3dd 4 to 6 weeks

Remarks:

SWAB remarks

Alternatief bij niet-IgE gemedieerde penicilline-allergie

Priority:
1st choice alternative
Medication:

ceftazidim iv 2000mg 3dd

+

tobramycine iv 5mg/kg 1dd

Remarks:

SWAB remarks

Bij punctieverwonding (spijker)

General comments

Aanpassen op geleide kweek.               

Na 2-3 wk switch naar oraal indien mogelijk op geleide kweek.

Punctieverwonding: dosering ceftazidim evt. verlagen op basis van MIC. Tobramycine totdat resistentiepatroon bekend is.   

Sources

TDM Alert
Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

External antimicrobial resources
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Metadata

Swab vid: G-6592.4
Updated: 04/05/2023 - 20:11
Status: Published